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1

Development of a fundamental '19-Sequence Model' of screenplay and narrative film structure

HEYES, MELVYN P.

Journal:

Journal of Screenwriting

Année:

2012

Langue:

english

Fichier:

PDF, 797 KB

english, 2012

2

Increased ratio of quinolinic acid to kynurenic acid in cerebrospinal fluid of D retrovirus—infected rhesus macaques: Relationship to clinical and viral status

Melvyn P. Heyes, Ivan N. Mefford, Bonnie J. Quearry, Manish Dedhia, Andrew Lackner

Journal:

Annals of Neurology

Année:

1990

Langue:

english

Fichier:

PDF, 996 KB

english, 1990

3

Quinolinic acid in cerebrospinal fluid and serum in HIV-1 Infection: Relationship to clinical and neurological status

Dr Melvyn P. Heyes, Bruce J. Brew, Alex Martin, Richard W. Price, Andres M. Salazar, John J. Sidtis, James A. Yergey, M. Maral Mouradian, Abigail E. Sadler, John Keilp, David Rubinow, Sanford P. Marke

Journal:

Annals of Neurology

Année:

1991

Langue:

english

Fichier:

PDF, 766 KB

english, 1991

4

Quinolinic acid in children with congenital hyperammonemia

Mark L. Batshaw, Michael B. Robinson, Keith Hyland, Sina Djali, Melvyn P. Heyes

Journal:

Annals of Neurology

Année:

1993

Langue:

english

Fichier:

PDF, 516 KB

english, 1993

5

Prospective study of neurological responses to treatment with macrophage-targeted glucocerebrosidase in patients with type 3 Gaucher's disease

Dr. Raphael Schiffmann, Melvyn P. Heyes, J. M. Aerts, James M. Dambrosia, Marc C. Patterson, Thomas DeGraba, Colette C. Parker, Gregory C. Zirzow, Katherine Oliver, Gioacchino Tedeschi, Roscoe O. Brad

Journal:

Annals of Neurology

Année:

1997

Langue:

english

Fichier:

PDF, 909 KB

english, 1997

6

Tryptophan metabolism via the kynurenine pathway in patients with the eosinophilia–Myalgia syndrome

Richard M. Silver, Kevin McKinley, Edwin A. Smith, Bonnie Quearry, Yadollah Harati, Esther M. Sternberg, Melvyn P. Heyes

Journal:

Arthritis & Rheumatism

Année:

1992

Langue:

english

Fichier:

PDF, 732 KB

english, 1992

7

(18O)quinolinic acid: Its esterification without back exchange for use as internal standard in the quantification of brain and CSF quinolinic acid

Melvyn P. Heyes, Sanford P. Markey

Journal:

Biological Mass Spectrometry = Journal of Mass Spectrometry (Wiley)

Année:

1988

Langue:

english

Fichier:

PDF, 316 KB

english, 1988

8

LC/MS Analysis of NAD Biosynthesis Using Stable Isotope Pyridine Precursors

Jason Evans, Tao-Chin Wang, Melvyn P. Heyes, S.P. Markey

Journal:

Analytical Biochemistry

Année:

2002

Langue:

english

Fichier:

PDF, 100 KB

english, 2002

9

Quantification of quinolinic acid in rat brain, whole blood, and plasma by gas chromatography and negative chemical ionization mass spectrometry: Effects of systemic l-tryptophan administration on brain and blood quinolinic acid concentrations

Melvyn P. Heyes, Sanford P. Markey

Journal:

Analytical Biochemistry

Année:

1988

Langue:

english

Fichier:

PDF, 935 KB

english, 1988

10

Quantification of kynurenic acid in cerebrospinal fluid: effects of systemic and central l-kynurenine administration

Melvyn P. Heyes, Bonnie J. Quearry

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Année:

1990

Langue:

english

Fichier:

PDF, 493 KB

english, 1990

11

Quantification of 3-hydroxykynurenine in brain by high-performance liquid chromatography and electrochemical detection

Melvyn P. Heyes, Bonnie J. Quearry

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Année:

1988

Langue:

english

Fichier:

PDF, 323 KB

english, 1988

12

Cerebrospinal Fluid Nitrite/Nitrate Levels in Neurologic Diseases

Sheldon Milstien, Naoki Sakai, Bruce J. Brew, Charles Krieger, James H. Vickers, Kuniaki Saito, Melvyn P. Heyes

Journal:

Journal of Neurochemistry

Année:

1994

Langue:

english

Fichier:

PDF, 307 KB

english, 1994

13

The Relationship Between Plasma and Brain Quinolinic Acid Levels and the Severity of Hepatic Encephalopathy in Animal Models of Fulminant Hepatic Failure

Anthony S. Basile, Kuniaki Saito, Yong Li, Melvyn P. Heyes

Journal:

Journal of Neurochemistry

Année:

1995

Langue:

english

Fichier:

PDF, 731 KB

english, 1995

14

Brain Quinolinic Acid in Chronic Experimental Hepatic Encephalopathy: Effects of an Exogenous Ammonium Acetate Challenge

Peter B. F. Bergqvist, Melvyn P. Heyes, Mogens Bugge, Finn Bengtsson

Journal:

Journal of Neurochemistry

Année:

1995

Langue:

english

Fichier:

PDF, 666 KB

english, 1995

15

Metabolism of l-Tryptophan to Kynurenate and Quinolinate in the Central Nervous System: Effects of 6-Chlorotryptophan and 4-Chloro-3-Hydroxyanthranilate

Dmitry B. Naritsin, Kuniaki Saito, S. P. Markey, Cai Y. Chen, Melvyn P. Heyes

Journal:

Journal of Neurochemistry

Année:

1995

Langue:

english

Fichier:

PDF, 901 KB

english, 1995

16

Quinolinic Acid Levels in a Murine Retrovirus-Induced Immunodeficiency Syndrome

Yoshitatsu Sei, Ian A. Paul, Kuniaki Saito, Richard Layar, Janet W. Hartley, Herbert C. Morse III, Phil Skolnick, Melvyn P. Heyes

Journal:

Journal of Neurochemistry

Année:

1996

Langue:

english

Fichier:

PDF, 636 KB

english, 1996

17

Quantification of Local De Novo Synthesis Versus Blood Contributions to Quinolinic Acid Concentrations in Brain and Systemic Tissues

Melvyn P. Heyes, Paul F. Morrison

Journal:

Journal of Neurochemistry

Année:

1997

Langue:

english

Fichier:

PDF, 847 KB

english, 1997

18

Species Heterogeneity Between Gerbils and Rats: Quinolinate Production by Microglia and Astrocytes and Accumulations in Response to Ischemic Brain Injury and Systemic Immune Activation

Melvyn P. Heyes, Kuniaki Saito, Cai Y. Chen, Margit G. Proescholdt, Thaddeus S. Nowak Jr., Ju Li, Karen E. Beagles, Martin A. Proescholdt, Mark A. Zito, Kensuke Kawai, Sanford P. Markey

Journal:

Journal of Neurochemistry

Année:

1997

Langue:

english

Fichier:

PDF, 1.26 MB

english, 1997

19

Quinolinic Acid In Vivo Synthesis Rates, Extracellular Concentrations, and Intercompartmental Distributions in Normal and Immune-Activated Brain as Determined by Multiple-Isotope Microdialysis

Karen E. Beagles, Paul F. Morrison, Melvyn P. Heyes

Journal:

Journal of Neurochemistry

Année:

1998

Langue:

english

Fichier:

PDF, 1.10 MB

english, 1998

20

Quinolinic Acid Is Extruded from the Brain by a Probenecid-Sensitive Carrier System: A Quantitative Analysis

Paul F. Morrison, Gregory M. Morishige, Karen E. Beagles, Melvyn P. Heyes

Journal:

Journal of Neurochemistry

Année:

1999

Langue:

english

Fichier:

PDF, 1.01 MB

english, 1999

21

Depletion of Systemic Macrophages by Liposome-Encapsulated Clodronate Attenuates Increases in Brain Quinolinic Acid During CNS-Localized and Systemic Immune Activation

Lutz A. Koennecke, Mark A. Zito, Margit G. Proescholdt, Nico Van Rooijen, Melvyn P. Heyes

Journal:

Journal of Neurochemistry

Année:

1999

Langue:

english

Fichier:

PDF, 368 KB

english, 1999

22

Effects of systemic and central nervous system localized inflammation on the contributions of metabolic precursors to the l-kynurenine and quinolinic acid pools in brain

Tomoyuki Kita, Paul F. Morrison, Melvyn P. Heyes, S. P. Markey

Journal:

Journal of Neurochemistry

Année:

2002

Langue:

english

Fichier:

PDF, 198 KB

english, 2002

23

[3H]1-[2-(2-thienyl)cyclohexyl]piperidine labels two high-affinity binding sites in human cortex: Further evidence for phencyclidine binding sites associated with the biogenic amine reuptake complex

Hyacinth C. Akunne, Audrey A. Reid, Andrew Thurkauf, Arthur E. Jacobson, Brain de Costa, Kenner C. Rice, Melvyn P. Heyes, Dr. Richard B. Rothman

Journal:

Année:

1991

Langue:

english

Fichier:

PDF, 1.23 MB

english, 1991

24

Viral load and its relationship to quinolinic acid, TNFα, and IL-6 levels in the CNS of retroviral infected mice

Rashed M. Nagra, Melvyn P. Heyes, Clayton A. Wiley

Journal:

Molecular and Chemical Neuropathology (Neurochemical Pathology)

Année:

1994

Langue:

english

Fichier:

PDF, 1.80 MB

english, 1994

25

Antibiotic-mediated release of tumour necrosis factor alpha and norharman in patients with hospital-acquired pneumonia and septic encephalopathy

Verena Eggers, Katja Fügener, Ortrud Vargas Hein, Hans Rommelspacher, Melvyn P. Heyes, Wolfgang J. Kox, Claudia D. Spies

Journal:

Intensive Care Medicine

Année:

2004

Langue:

english

Fichier:

PDF, 178 KB

english, 2004

26

Rapid identification of correctly located intracerebroventricular cannula in the rat

Melvyn P. Heyes, Stephen Garnett, Geoffery Coates

Journal:

Journal of Neuroscience Methods

Année:

1983

Langue:

english

Fichier:

PDF, 240 KB

english, 1983

27

Systemic Lipopolysaccharide and Pokeweed Mitogen Increase Quinolinic Acid Content of Mouse Cerebral Cortex

Melvyn P. Heyes, Phillip Kim, Sanford P. Markey

Journal:

Journal of Neurochemistry

Année:

1988

Langue:

english

Fichier:

PDF, 252 KB

english, 1988

28

Brain and Plasma Quinolinic Acid in Profound Insulin-Induced Hypoglycemia

Melvyn P. Heyes, Marios Papagapiou, Catherine Leonard, Sanford P. Markey, Roland N. Auer

Journal:

Journal of Neurochemistry

Année:

1990

Langue:

english

Fichier:

PDF, 798 KB

english, 1990

29

Increased Cerebrospinal Fluid Quinolinic Acid, Kynurenic Acid, and L-Kynurenine in Acute Septicemia

Melvyn P. Heyes, Andrew Lackner

Journal:

Journal of Neurochemistry

Année:

1990

Langue:

english

Fichier:

PDF, 478 KB

english, 1990

30

Kynurenine Pathway Enzymes in Brain: Responses to Ischemic Brain Injury Versus Systemic Immune Activation

Kuniaki Saito, Thaddeus S. Nowak Jr., Kazuhiko Suyama, Bonnie J. Quearry, Misato Saito, Jeffrey S. Crowley, Sanford P. Markey, Melvyn P. Heyes

Journal:

Journal of Neurochemistry

Année:

1993

Langue:

english

Fichier:

PDF, 1.06 MB

english, 1993

31

Mechanism of Delayed Increases in Kynurenine Pathway Metabolism in Damaged Brain Regions Following Transient Cerebral Ischemia

Kuniaki Saito, Thaddeus S. Nowak Jr., Sanford P. Markey, Melvyn P. Heyes

Journal:

Journal of Neurochemistry

Année:

1993

Langue:

english

Fichier:

PDF, 1.39 MB

english, 1993

32

Delayed Increases in Regional Brain Quinolinic Acid Follow Transient Ischemia in the Gerbil

Heyes, Melvyn P., Nowak, Thaddeus S.

Journal:

Journal of Cerebral Blood Flow and Metabolism

Année:

1990

Langue:

english

Fichier:

PDF, 440 KB

english, 1990

33

Brain Eicosanoid Formation Following Acute Penetration Injury as Studied by In Vivo Microdialysis

Heyes, Melvyn P., Yergey, James A.

Journal:

Journal of Cerebral Blood Flow and Metabolism

Année:

1990

Langue:

english

Fichier:

PDF, 227 KB

english, 1990

34

Quinolinic Acid Is Increased in CSF and Associated With Mortality After Traumatic Brain Injury in Humans

Sinz, Elizabeth H., Kochanek, Patrick M., Heyes, Melvyn P., Wisniewski, Stephen R., Bell, Michael J., Clark, Robert S. B., DeKosky, Steven T., Blight, Andrew R., Marion, Donald W.

Journal:

Journal of Cerebral Blood Flow and Metabolism

Année:

1998

Langue:

english

Fichier:

PDF, 419 KB

english, 1998

35

Brain extracellular quinolinic acid in chronic experimental hepatic encephalopathy as assessed by in vivo microdialysis: Acute effects of L-tryptophan

Peter B.F. Bergqvist, Melvyn P. Heyes, Gustav Apelqvist, Roger F. Butterworth, Finn Bengtsson

Journal:

Neuropsychopharmacology

Année:

1996

Langue:

english

Fichier:

PDF, 805 KB

english, 1996

36

Depletion of systemic macrophages by liposome-encapsulated clodronate attenuates striatal macrophage invasion and neurodegeneration following local endotoxin infusion in gerbils

Mark A. Zito, Lutz A. Koennecke, Matthew J. McAuliffe, Bevin McNally, Nico van Rooijen, Melvyn P. Heyes

Journal:

Année:

2001

Langue:

english

Fichier:

PDF, 5.56 MB

english, 2001

37

Sensorineural hearing loss from quinolinic acid: A neurotoxin in middle ear effusions

Robert F. Yellon, Elizabeth Rose, Margaret A. Kenna, William J. Doyle, Margaretha Casselbrant, Warren F. Diven, Theresa L. Whiteside, J. Douglas Swarts, Melvyn P. Heyes

Journal:

The Laryngoscope

Année:

1994

Fichier:

PDF, 722 KB

1994

38

Systemic endotoxin increasesl-tryptophan, 5-hydroxyindoleacetic acid, 3-hydroxykynurenine and quinolinic acid content of mouse cerebral cortex

Melvyn P. Heyes, Bonnie J. Quearry, Sanford P. Markey

Journal:

Année:

1989

Langue:

english

Fichier:

PDF, 523 KB

english, 1989

39

Cytokine-induced activation of the neuroendocrine stress axis persists in endotoxin-tolerant mice

Ivan N. Mefford, Carolyn F. Masters, Melvyn P. Heyes, Robert L. Eskay

Journal:

Année:

1991

Langue:

english

Fichier:

PDF, 357 KB

english, 1991

40

Cerebral cortex and lung indoleamine-2,3-dioxygenase activity is increased in type-D retrovirus infected macaques

Kuniaki Saito, Andrew Lackner, Sanford P. Markey, Melvyn P. Heyes

Journal:

Année:

1991

Langue:

english

Fichier:

PDF, 368 KB

english, 1991

41

Chronic effects of γ-interferon on quinolinic acid and indoleamine-2,3-dioxygenase in brain of C57BL6 mice

Kuniaki Saito, Sanford P. Markey, Melvyn P. Heyes

Journal:

Année:

1991

Langue:

english

Fichier:

PDF, 405 KB

english, 1991

42

Relationship of neurologic status in macaques infected with the simian immunodeficiency virus to cerebrospinal fluid quinolinic acid and kynurenic acid

Melvyn P. Heyes, Elaine K. Jordan, Kristin Lee, Kuniaki Saito, Joseph A. Frank, Phillip J. Snoy, Sanford P. Markey, Maneth Gravell

Journal:

Année:

1992

Langue:

english

Fichier:

PDF, 4.25 MB

english, 1992

43

Increased levels of the excitotoxin quinolinic acid in spinal cord following contusion injury

Andrew R. Blight, Kuniaki Saito, Melvyn P. Heyes

Journal:

Année:

1993

Langue:

english

Fichier:

PDF, 286 KB

english, 1993

44

Neuroactive metabolises of L-tryptophan, serotonin and quinolinic acid, in striatal extracellular fluid effect of tryptophan loading

Matthew J. During, Andrew Freese, Melvyn P. Heyes, Kenton J. Swartz, Stanford P. Markey, Robert H. Roth, Joseph B. Martin

Journal:

Année:

1989

Langue:

english

Fichier:

PDF, 655 KB

english, 1989

45

Identification of a battery of tests for drug candidate evaluation in the SMNΔ7 neonate model of spinal muscular atrophy

Bassem F. El-Khodor, Nicole Edgar, Angela Chen, Margaret L. Winberg, Cynthia Joyce, Daniela Brunner, Mayte Suárez-Fariñas, Melvyn P. Heyes

Journal:

Experimental Neurology

Année:

2008

Langue:

english

Fichier:

PDF, 2.31 MB

english, 2008

46

Cerebrospinal Fluid and Serum Markers of Inflammation in Autism

Andrew W. Zimmerman, Harumi Jyonouchi, Anne M. Comi, Susan L. Connors, Sheldon Milstien, Angeliki Varsou, Melvyn P. Heyes

Journal:

Pediatric Neurology

Année:

2005

Langue:

english

Fichier:

PDF, 134 KB

english, 2005

47

Immune Activation in Autism: Reply

Andrew W. Zimmerman, Susan L. Connors, Harumi Jyonouchi, Sheldon Milstien, Melvyn P. Heyes

Journal:

Pediatric Neurology

Année:

2006

Langue:

english

Fichier:

PDF, 41 KB

english, 2006

48

U50,488 protection against HIV-1-related neurotoxicity: involvement of quinolinic acid suppression

Chun C. Chao, Shuxian Hu, Genya Gekker, James R. Lokensgard, Melvyn P. Heyes, Phillip K. Peterson

Journal:

Neuropharmacology

Année:

2000

Langue:

english

Fichier:

PDF, 418 KB

english, 2000

49

Cerebrospinal fluid tau protein is not elevated in HIV-associated neurologic disease in humans

Ronald J Ellis, Peter Seubert, Ruth Motter, Douglas Galasko, Reena Deutsch, Robert K Heaton, Melvyn P Heyes, J.Allen McCutchan, J Hampton Atkinson, Igor Grant

Journal:

Neuroscience Letters

Année:

1998

Langue:

english

Fichier:

PDF, 57 KB

english, 1998

50

Cerebrospinal fluid levels of kynurenine pathway metabolites in patients with eating disorders: Relation to clinical and biochemical variable

Mark A. Demitrack, Melvyn P. Heyes, Margaret Altemus, Teresa A. Pigott, Philip W. Gold

Journal:

Biological Psychiatry

Année:

1995

Langue:

english

Fichier:

PDF, 779 KB

english, 1995